Cascara Sagrada is Spanish for "sacred bark," and is a botanical bowel stimulant, used in Western herbal medicine and scientifically studied for 125+ years to stimulate muscular movement of the gut, and to shorten and regulate bowel transit time, encouraging complete and regular emptying of the bowels.

As clinicians, we've successfully used Cascara Sagrada, and Debloat Detox in general on 10's of thousands of people who suffer from a sluggish, constipated bowel.

Cascara also contains high amounts of a substance called Emodin, which has a wide range of biological activities, including diuretic, antibacterial, anti-ulcer, anti-inflammatory, and anticancer. In the present work the potential therapeutic role of emodin in treatment of inflammatory diseases, cancers, and microbial infections is analyzed.

References:

125+ years of scientific research - 1

Benefits of Emodin (a compound found in Cascara) - 2, 3

An extraordinary anti-inflammatory botanical used to bloating, belly distention and dyspepsia (belching, burping, excess gas). Chamomile also reduces the severity and duration of diarrhoea.

The best plant-based medicines not only have excellent therapeutic effects, but they also can help us to feel better about ourselves and our situations. Chamomile also helps to reduce anxiety, a common side-effect of gastrointestinal symptoms like bloating and constipation.

References:

Anti-inflammatory, bloat reducing - 1, 2, 3

Reduces diarrhoea - 4, 5

Anxiety lowering - 6, 7

St. Mary's Thistle or "milk thistle" is a powerful protector of the liver and is regularly used as a complementary therapy by people who have liver damage due to conditions like alcoholic liver disease, non-alcoholic fatty liver disease, hepatitis, and even liver cancer.

It also helps to protect the liver against toxins and reduces liver inflammation.

References:

Protects the liver - 1, 2, 3.

Protects the liver from toxins and reduces inflammation - 4, 5, 6.

Fennel has a long history of traditional medicine use for IBS, stomach aches, flatulence, diarrhea, constipation, and as an anti-fungal / anti-bacterial.

Its wide-ranging positive effects on gut health are due to the high levels of powerful active ingredients contained within Fennel, like the flavanoids quercetin, apigenin, rosmarinic acid, and limonene, along with other vitamins and trace minerals.

Fennel helps lower oxidative stress (created when cells in your body lose electrons making free radicals) by increasing the content/activities of liver detoxification enzymes, and the activity of antioxidants like superoxide dismutase. Fennel also reduces inflammation by reducing the production of inflammatory cytokines like TNF-alpha. Furthermore, Fennel has been found to help increase the proteins that cause cancer cell death

References:

Gut health - 1, 2, 3, 4, 5

Lowering cellular stress + inflammation 6, 7, [8, 9, 10.

Increasing cancer cell death - 11, 12

Senna leaf has been used for centuries to help treat constipation. Senna helps to stimulate the natural contractions of your gut, called peristalsis.

Senna also helps to increase stool frequency and weight, as well as reduce hemorrhoids.

References:

Senna reduces constipation, stool frequency, and stool weight - 1, 2, 3

Senna helps reduce hemorrhoids - 4