Gut Health

New Pre-Clinical Research:
How Collagen Peptides May Support
Your Body’s Natural Satiety Signals

Written By: Dr Marie-Aurore Caillaud

Published at: 04/09/2026

Updated at: 04/09/2026

Gut Smarter

At My Way Up®, we believe the best health decisions are informed ones. That’s why we invest in research to better understand how our ingredients interact with the body — so we can continue to develop products grounded in science, not trends.

We recently commissioned a pre-clinical study to explore how the collagen peptides used in our formulations interact with GLP-1, a naturally occurring hormone that plays an important role in digestive function and satiety.

Here’s what we learned, what it means, and what comes next.

What is GLP-1?

Glucagon-like peptide 1 (GLP-1) is a hormone produced naturally by cells in your gut after you eat. It’s part of the body’s built-in signalling system and plays several roles in digestion and metabolic function:

Satiety signalling: GLP-1 communicates with the brain to help regulate feelings of fullness after a meal.

Digestive pacing: It helps modulate the rate at which food moves through the stomach, supporting comfortable digestion.

Blood sugar regulation: GLP-1 supports the body’s natural insulin response as part of normal post-meal glucose management.

Gut barrier support: Emerging research suggests GLP-1 may play a role in maintaining the integrity of the gut lining.

GLP-1 is the subject of significant scientific interest globally. Researchers across multiple disciplines are exploring how diet, specific nutrients, and lifestyle factors influence the body’s natural GLP-1 production.

About the Study

We commissioned an independent pre-clinical study to investigate how the specific collagen hydrolysate used in Collagen Restore™ interacts with GLP-1 pathways. The study was conducted in a controlled laboratory setting using specialised intestinal cell models.

Important context: This was a pre-clinical (in vitro) study, meaning it was conducted on cell cultures in a laboratory — not in humans. Pre-clinical research is a valuable early step in understanding how ingredients behave at a cellular level, but results observed in the lab do not automatically translate to the same effects in the human body. Further research, including clinical trials in humans, would be needed to confirm these findings.

What We Observed

In the laboratory setting, the collagen hydrolysate used in Collagen Restore™ was compared against standard reference compounds (glucose and alpha-linolenic acid) that are known to stimulate GLP-1 secretion in cell models.

GLP-1 secretion: The collagen hydrolysate stimulated measurably higher GLP-1 release from the intestinal cells compared to the reference compounds tested.

DPP-4 interaction: GLP-1 is normally broken down rapidly by an enzyme called DPP-4. The study observed that the collagen hydrolysate appeared to slow this breakdown in the cell model, which is an area of particular interest for further research.

These observations are encouraging and support the rationale for further investigation into how collagen peptides interact with gut hormone pathways.

Why We Invest in Research

As a gut health company built on shotgun metagenomic testing, we believe in a science-first approach. Commissioning pre-clinical research like this is part of our ongoing commitment to understanding — at a deeper level — how the ingredients in our products interact with the body.

This study adds to a growing body of published research exploring the relationship between dietary peptides and gut hormone signalling. It also informs how we think about future formulation development.

We’ll continue to invest in this research and share our findings transparently as the science evolves.

Collagen Restore™

An advanced Australian-sourced collagen peptide formula made with clinically-studied prebiotic Bimuno GOS to improve gut health in as little as 7 days.

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About Collagen Restore™

Collagen Restore™ combines high-quality collagen hydrolysate with Bimuno® GOS (a well-researched prebiotic) and zinc to support skin, gut health, and overall wellbeing. It’s designed to be added to your morning coffee, a smoothie, or breakfast.

As a food product, Collagen Restore™ is formulated to support general health and wellbeing as part of a balanced diet. It is not intended to diagnose, treat, cure, or prevent any disease.

Editorial Standards

My Way Up® has strict sourcing guidelines to ensure our content is accurate and current. We rely on peer-reviewed studies, academic research institutions, and medical associations.

The information in this article is based on pre-clinical (in vitro) research and is provided for educational and informational purposes only. Pre-clinical results do not constitute evidence of efficacy in humans. This content does not constitute medical advice and should not be used as a substitute for professional healthcare guidance. Collagen Restore™ is a food product and is not a therapeutic good. It is not intended to diagnose, treat, cure, or prevent any disease or medical condition. Always consult your healthcare professional before making changes to your diet or supplement routine.