Gut Health

    The Gut–Brain Axis: How Your Microbiome Shapes Your Mood

    Written By: Georgia Plagakis
    Published at: 10/23/2025
    Updated at: 10/23/2025

    Gut Smarter

    We often think of the gut and brain as two separate systems - one in charge of digestion, the other in charge of thoughts and feelings. But research shows they’re deeply connected through what’s called the gut–brain axis [1].

    This is a two-way communication network that links your digestive tract and central nervous system through nerves, immune signals, hormones, and importantly - the microbiome [1,2].

    In this article we break down the role your microbiome plays in influencing your mood and how you can boost this interplay, by boosting your gut health.

    Your Microbiome: the Missing Link

    Your gut is home to trillions of microbes which actively produce compounds that influence your brain and mood [3].

    Through the vagus nerve: This “information superhighway” runs between your gut and brain. Signals from gut microbes can stimulate the vagus nerve and directly affect brain regions involved in mood and stress regulation [1].

    Through microbial metabolites: Gut bacteria produce short-chain fatty acids (like butyrate) and other compounds that help regulate inflammation and support healthy brain function [2].

    Through tryptophan availability: Gut microbes influence how much tryptophan (the building block of serotonin) reaches the brain, where it can be converted into mood-regulating neurotransmitters [4].

    Through immune balance: When the gut is out of balance, it can contribute to ongoing immune activation and inflammation, which may affect brain signaling and is often associated with low mood, brain fog, and fatigue. A healthy gut microbiome helps regulate immune responses and plays a key role in supporting healthy brain function [1,2].

    The takeaway? A healthy, diverse gut microbiome is one of the most powerful (and underrated) ways to support mental wellbeing.


    How to Strengthen the Gut–Brain Connection

    Building a balanced microbiome isn’t about quick fixes -  it’s about daily habits that feed, protect, and restore your gut ecosystem. That means eating a variety of whole foods, getting enough fibre, cutting back on ultra-processed foods, and supporting your gut with targeted nutrients [5].

    Where Daily Gut™ fits in

    This is why we created Daily Gut™, a complete, multi-action gut health formula designed not just to support gut function, but also to support mood and the gut–brain axis.

    It combines:

    • Prebiotics (Sunfiber® and Fibergum™) to feed beneficial microbes.

    • Probiotics (Lactospore® bacillus coagulans and Saccharomyces boulardii) to reinforce balance in the microbiome.

    • Polyphenols (from pomegranate, green tea, wild blueberry, and blue spirulina) to nourish the microbiome, reduce oxidative stress and calm inflammation [5].

    • Botanicals (aloe vera and marshmallow root) to soothe and protect the gut lining.

    • Amino acids (L-glutamine and L-glycine) to fuel repair of the gut barrier.

    All in one easy daily scoop.

    Because when your gut thrives, your brain does too.

    Daily Gut

    Probiotic + prebiotic formula to support gut function + mood

    The Bottom Line

    • Your gut talks to your brain. The gut–brain axis links digestion and mood via nerves (vagus), immune signals, hormones, and the microbiome.

    • Microbes influence mood. Gut bacteria affect inflammation, make metabolites (e.g., SCFAs), shape tryptophan/serotonin availability, and can shift brain signaling tied to stress, brain fog, and fatigue.

    • Build a resilient microbiome. Daily habits—diverse whole foods, more fiber, fewer ultra-processed foods—and targeted prebiotics/probiotics/polyphenols can strengthen the gut–brain connection and support mental well-being.

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    My Way Up® has strict sourcing guidelines to ensure our content is accurate and current. We rely on peer-reviewed studies, academic research institutions, and medical associations.

    This article is for informational purposes only and does not constitute medical advice. The information contained herein is not a substitute for and should never be relied upon for professional medical advice. Always talk to your doctor about the risks and benefits of any treatment.