Disclaimer: This blog is for general informational purposes only and does not constitute medical advice. The information provided is not intended to diagnose, treat, cure, or prevent any disease. Results may vary from person to person. Always consult your healthcare professional before starting any new supplement, particularly if you are pregnant, breastfeeding, have a medical condition, or are taking medication. Always read the label and follow directions for use.
Problem Skin
Do Gut-Skin Axis Supplements Really Work? The Research on Clearer Skin, Less Bloating, and Fewer Flare-Ups
Reviewed By:
Cody Martin - BHSc [Naturopathy]
Written By:
Alice Crabb - Naturopath
Published at:
10/12/2026
Updated at:
10/12/2026
Best Gut-Skin Axis Supplements at a Glance
Clearer skin may start in your gut. Research links gut microbiome imbalance to acne, eczema and psoriasis, and gut-skin supplements target that link from within. Everyone’s different and the science is still evolving, but most reviewers notice a difference within weeks to months of daily use.
THE SHORT VERSION
- The gut-skin axis is a researched pathway: gut microbiome imbalance may be linked to internal changes that can show up as acne, eczema or psoriasis.
- Skin + Gut™ is intended to address acne, mild eczema and mild psoriasis.
- Collagen Restore™ is designed to restore skin, gut and hair, with reviewers noting reduced bloating and improved skin quality.
- Both come from My Way Up®, an Australian gut health company with a gut-first, science-backed approach.
- Results need consistent daily use. Reviewer timelines range from 7–10 days to several months.
This is general information - always talk to your doctor about what's right for you. If your symptoms persist or worsen, please see your healthcare professional.
What Is the Gut-Skin Axis?
Ever noticed your skin flare up after a week of poor sleep, stress or eating differently? That may be the gut-skin axis at work.
The gut-skin axis is the researched link between your gut microbiome and your skin. Research has identified correlations between gut dysbiosis (an imbalanced gut microbiome) and conditions including acne, eczema and psoriasis, though the exact mechanisms are still being studied (1, 2).
Your gut lining acts as a filter - thinner than tissue paper, but responsible for deciding what gets through. When that barrier is compromised, the body's immune responses can become dysregulated. Your skin, as your largest organ, often reflects these internal shifts first.
Reviews of the research describe the gut microbiome as a major regulator of the gut-skin axis, influencing the immune system in ways that may affect the skin (1). Studies have found differences in the gut microbiome of people with acne, eczema (atopic dermatitis) and psoriasis, and researchers are exploring whether probiotics, prebiotics and diet can help restore balance (2). Much of this research is still early, which is why results vary from person to person.
The gut-skin axis isn't a light switch - it's a dimmer dial. Your body needs time to rebalance.
Does Skin + Gut™ Help With Acne, Eczema and Psoriasis?
Skin + Gut™ ($69.99) is intended to address acne, mild eczema and mild psoriasis. Rather than offering general gut support, it targets these conditions specifically, working through the gut microbiome. Its key ingredient is polaprezinc (zinc-carnosine), studied for its role in supporting gut lining integrity. It also contains the probiotic Saccharomyces boulardii (1 billion CFU), plus zinc, copper, beta-carotene and vitamin B5 for skin health. My Way Up recommends a minimum 90-day course.
One mother reported her teenage son "has seen a significant improvement in his acne" after 3 months of daily use (Kellie S.). A reviewer with psoriasis said "the results were visible within 7-10 days" (Ilya S.). That's the fast end of the range - most reviewers describe meaningful change over weeks to months.
Skin + Gut™
Target skin issues at the source for clear skin from within.
- Relieves acne + blackheads
- Relieves mild eczema/psoriasis symptoms
- Heals + repairs the skins surface**
Does Collagen Restore™ Help With Bloating and Skin Quality?
Collagen Restore™ ($69.99) is an Australian-made collagen peptide formula designed to restore skin, gut and hair. Each serve contains 7.2 g of grass-fed bovine collagen peptides, plus a GOS prebiotic, organic bamboo silica and zinc. The collagen peptides focus on skin, while the GOS prebiotic feeds beneficial gut bacteria - the ingredient behind the formula's gut-comfort focus. Emerging research suggests collagen peptides may play a supportive role in gut and skin health (3). Compared with Skin + Gut™, it is less targeted at specific conditions and more focused on foundational gut comfort and skin nourishment.
Reviewers describe a consistent pattern: gut comfort improves first, bloating reduces, and skin quality follows. After 9 months of daily use, one reviewer reported improvements in "gut health, skin hydration and elasticity" (Renee L.). Another, using it for over a year, reported "no more bloating or gut issues" (Cheryl M.).
Collagen Restore™
Australia's most advanced collagen peptide formula for skin + gut health.
- Smooth, hydrated skin
- Skin collagen formation + density
- Better gut health in 7 days
Which Gut-Skin Supplement Should You Choose?
It depends on your main concern.
- Acne, eczema or psoriasis: Skin + Gut™, which targets these conditions specifically.
- Skin quality, bloating, or hair and nail strength: Collagen Restore™. One reviewer said her "broken, chipped and flaky nails" stopped breaking after about 2 months (Pam M.).
Can you use both together? Yes. Skin + Gut™ targets specific skin conditions, while Collagen Restore™ supports overall skin quality and gut comfort. Several reviewers use both as a complementary approach.
Whichever you choose, results take weeks to months of consistent daily use. This isn't a one-week fix.
